Christine Campbell (Julia Louis-Dreyfus) is a single mom. She owns a women's gym and spends time worrying about her son and pretty much everything else around her. A frequent fixture in her life is her ex-husband Richard (Clark Gregg), whose new girlfriend is also named Christine, therefore relegating her to be the old Christine. She keeps sane with her best friend (Wanda Sykes) and her brother (Hamish Linklater) by her side.